Teaching T cells to hunt cancer spurred remissions in two kinds of leukemia. A new study suggests the technique may also work to treat glioblastoma, a type of brain cancer.
Today's study, published in Science Translational Medicine , describes a range of tests to determine a target for the immune system in glioblastoma. The protein, called EGFRvIII, occurs in about a third of glioblastomas. On the basis of the study's results, the researchers are moving into human testing.
In this method of treatment, scientists harvest the blood of a person with cancer. Then, in the lab, they use a gene transfer to teach the T cells to target a specific protein. The engineered T cells are then transplanted back into the patient. In the case of blood...
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