Mice could slowly be replaced with monkeys as the prime animal subjects for human illness research. Scientists in China have successfully bred the first monkeys with targeted genetic mutations, which could lead to primates modeling sicknesses found in humans.
The team from Model Animal Research Center of Nanjing University led by geneticist Xingxu Huang first targeted three specific genes in a monkey cell line in the experiment, and were able to disrupt them about 10 to 25 percent of the time. They then targeted genes in 180 single-cell monkey embryos, and implanted 83 of them in living mothers. Those implantations yielded ten pregnancies — and only one birth. It was not an easy task, but the newborn twin female primates are a hopeful...
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