The search for an effective vaccine to protect against HIV has hit yet another roadblock. A major clinical trial on what was once deemed a potential blockbuster strategy has been halted by federal researchers, after it was determined that the approach didn't prevent infection among study participants.
The trial, which kicked off in 2009 and included around 2,500 participants, set out to evaluate a vaccine called HVTN-505. The vaccine relied on a weakened version of a common cold virus, called Ad5, which operated as a vehicle to carry key HIV genes into the body and prime the immune system to defend against the illness. It's an approach that's been tried unsuccessfully before, namely in a 2007 trial, called STEP, that also ended early.
via The Verge - All Posts http://www.theverge.com/2013/4/26/4270482/setback-for-hiv-vaccine-major-clinical-trial-shut-down
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